Structural Evidence for Asymmetrical Nucleotide Interactions in Nitrogenase
نویسندگان
چکیده
منابع مشابه
Structural Evidence for Asymmetrical Nucleotide Interactions in Nitrogenase
The roles of ATP hydrolysis in electron-transfer (ET) reactions of the nitrogenase catalytic cycle remain obscure. Here, we present a new structure of a nitrogenase complex crystallized with MgADP and MgAMPPCP, an ATP analogue. In this structure the two nucleotides are bound asymmetrically by the Fe-protein subunits connected to the two different MoFe-protein subunits. This binding mode suggest...
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The three approaches to too-many-solutions problems discussed in the previous chapter do not treat them as symptomatic of significant generalizations about input-output mappings rather than outputs. Because this systematic challenge to OT is not recognized, previous attacks on these problems, apart from de Lacy's general proposal, see them as an assortment of individual difficult cases and anal...
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INTRODUCTION .......................................... 235 PROPERTIES OF THE NITROGENASE PROTEINS ................... 237 Fe-Protein ............................................ 238 MoFe-Protein .......................................... 241 Species-Specific Variations in Nitrogenase Proteins ................... 245 GENETICS AND ASSEMBLY OF TIIE NITROGENASE PROTEINS ........ 246 MECHANISM OF N...
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Examination of interactions among various substrates and inhibitors reacting with a partially purified nitrogenase from Azotobacter vinelandii has shown that: nitrous oxide is competitive with N2; carbon monixide and acetylene are noncompetitive with N2; carbon monoxide, cyanide, and nitrous oxide are noncompetitive with acetylene, whereas N2 is competitive with acetylene; carbon monoxide is no...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2014
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja511945e